Conan O'Brien and his lovely wife at Vanity Fair

Liza Powel O'Brien Chats About "Significant Others" | Conan O’Brien Needs a Friend

All scenes of Liza Powel O'Brien in Conan O'Brien can't stop

teenage conan o'brien interviewing siblings

Conan’s Wife Liza Introduces “Significant Others’ Season Two | Conan O'Brien Needs A Friend

The Greatest Takedown in Talk Show History: Conan Brutally Corrects Jennifer Garner | Conan

Conan's Daughter | Late Night with Conan O’Brien

John Cleese and Eric Idle's Secrets To A Perfect Marriage | CONAN on TBS

Both Dax Shepard & Conan Have Wives Who Are Too Attractive For Them | CONAN on TBS

Conan's Creepiest Moment Ever - 1/2/07

Conan O'Brien and his son Beckett

J.Y. Park "Fire" feat. Conan O'Brien & Steven Yeun & Jimin Park Official M/V | CONAN on TBS

Jodie Foster: Jeff Goldblum Is A Walking Lawsuit | CONAN on TBS

Jeff Goldblum On His Wife’s Sweet Nickname For Him | CONAN on TBS

Chelsea Peretti's Childhood Crush On Andy Samberg | CONAN on TBS

Timothy Olyphant Was An Artsy Jock In College | CONAN on TBS

Lisa Kudrow Attended Conan’s "Late Night" Audition | Late Night with Conan O’Brien

John Krasinski Didn't Think He'd Get A Second Date With Emily Blunt | CONAN on TBS

Jon Stewart & Stephen Colbert Crash Conan NYC | CONAN on TBS

Conan & Sona Celebrate 15 Years Of Working Together | Conan O'Brien Needs A Friend