Demystifying Xenotransplantation: CRISPR Gene Editing Explained. Part 3

This video is part of a three part series on how the pig to human heart transplantation was made possible. This video is the third and last part of the series and explores how through the use of CRISPR Gene editing, the pig heart was made viable to be transplanted into a human body. More specifically, the video outlines a refresher on CRISPR biotechnology, how it works, how it was specifically used in the pig heart transplant, possible Implications or downsides of CRISPR, other current medical treatments and projects that are using CRISPR CAS9 technology.

Here are the links to the previous two video of this three part series:

Demystifying Xenotransplantation Part 1: https://youtu.be/LpVMT5gDwa8

Demystifying Xenotransplantation Part 2: https://youtu.be/qtlzboCp1GU

This video was made by McMaster students Chethana Ellewela, Nidal Jammal, Ravni Bomrah, and Yashasvi Yadav in collaboration with the McMaster Demystifying Medicine Program.

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This video is provided for general and educational information only.

Copyright McMaster University 2022.

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Sources:
https://actionagainsthunger.ca/what-is-acute-malnutrition/underlying-causes-of-malnutrition/
https://www.medicalnewstoday.com/articles/179316#risk
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https://www.hsph.harvard.edu/nutritionsource/microbiome/
https://www.healthline.com/nutrition/gut-microbiome-and-health#TOC_TITLE_HDR_3
https://www.youtube.com/watch?v=6tw_JVz_IEc
https://www.technologyreview.com/2022/01/11/1043374/gene-edited-pigs-heart-transplant/
https://www.science.org/content/article/here-s-how-scientists-pulled-first-pig-human-heart-transplant
https://www.science.org/content/article/first-gene-editing-treatment-injected-blood-reduces-toxic-protein-1-year
https://www.frontiersin.org/articles/10.3389/fonc.2020.01387/full
https://protomag.com/transplants/four-breakthroughs-that-led-to-the-pig-heart-transplant/
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