H2 Blockers (Cimetidine, Ranitidine, Famotidine, Nizatidine) Mnemonic for USMLE
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H2 receptor blockers or H2 antagonists are drugs that block the action of histamine at H2 receptors in the stomach. This drug class includes cimetidine, ranitidine, and famotidine. Blocking histamine at H2 receptors notably decreases stomach acid production, which can be used to treat acid-mediated disorders like peptic ulcer disease and gastroesophageal reflux disease. Importantly, the drug cimetidine has a few notable side effects. Cimetidine is a powerful CYP enzyme inhibitor that can lead to various drug interactions. Cimetidine also has anti-androgenic effects, which can lead to gynecomastia.
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#USMLE #Step1 #Pharm #H2Blockers
0:00 Introduction
0:26 Block H2 Receptors (misthrown horseshoes. H2)
1:14 Cimetidine (cemetery)
1:30 Ranitidine
2:31 Treats Peptic Ulcer (hole in shirt)
3:44 Treats Acid Reflux / GERD (spitting beer)
4:31 Cimetidine: Inhibits CYP Enzymes (beer bong - sip inhibition)
5:25 Cimetidine: Causes Gynecomastia (coconut bra)
H2 receptor blockers or H2 antagonists are drugs that block the action of histamine at H2 receptors in the stomach. This drug class includes cimetidine, ranitidine, and famotidine. Blocking histamine at H2 receptors notably decreases stomach acid production, which can be used to treat acid-mediated disorders like peptic ulcer disease and gastroesophageal reflux disease. Importantly, the drug cimetidine has a few notable side effects. Cimetidine is a powerful CYP enzyme inhibitor that can lead to various drug interactions. Cimetidine also has anti-androgenic effects, which can lead to gynecomastia.
Subscribe for more: https://bit.ly/2yybxhm
Study interactive image: https://pixorize.com/view/6012
#USMLE #Step1 #Pharm #H2Blockers
0:00 Introduction
0:26 Block H2 Receptors (misthrown horseshoes. H2)
1:14 Cimetidine (cemetery)
1:30 Ranitidine
2:31 Treats Peptic Ulcer (hole in shirt)
3:44 Treats Acid Reflux / GERD (spitting beer)
4:31 Cimetidine: Inhibits CYP Enzymes (beer bong - sip inhibition)
5:25 Cimetidine: Causes Gynecomastia (coconut bra)
